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Witch broom sign is a radiological finding that refers to an abnormal appearance of the cerebellum on imaging studies, specifically magnetic resonance imaging (MRI). The term "witch broom" is used to describe the pattern seen on axial MRI images, where the cerebellum appears divided into multiple lobes with prominent cerebellar folia, resembling the bristles of a broom. This sign is most commonly observed in certain genetic disorders known as Joubert syndrome and related conditions. Joubert syndrome is a rare autosomal recessive disorder characterized by a molar tooth sign on MRI, which refers to the appearance of the midbrain and hindbrain resembling a molar tooth. The witch broom sign is often seen in association with the molar tooth sign in these patients. The witch broom sign is believed to be due to abnormal cerebellar development during embryogenesis.

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The witch broom sign is believed to be due to abnormal cerebellar development during embryogenesis. The cerebellum is responsible for coordinating movements and maintaining balance, and any abnormalities in its structure can lead to various neurological symptoms. In addition to Joubert syndrome, the witch broom sign has also been reported in other conditions such as rhombencephalosynapsis and pontocerebellar hypoplasia.

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These conditions are all part of a spectrum of cerebellar disorders characterized by varying degrees of cerebellar hypoplasia or malformation. In conclusion, the witch broom sign is a radiological finding observed on MRI, indicating an abnormal appearance of the cerebellum. It is most commonly seen in Joubert syndrome and related disorders, and is believed to be a result of abnormal cerebellar development. Further research is needed to better understand the underlying mechanisms and clinical implications of this sign..

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uncle majic jail