Magic mac nitrogen is a concept that refers to the magical properties and uses of nitrogen, a chemical element found abundantly in the Earth's atmosphere. Nitrogen is a vital component for life as it is an essential element in proteins and DNA. However, its magical properties go beyond its biological significance. One of the magical properties of nitrogen is its ability to transform substances with its chemical reactivity. Nitrogen gas can react with various elements and compounds to form new substances. For example, when nitrogen reacts with oxygen in the air under high temperature and pressure, it forms nitrogen oxides, which are important components in the formation of rain, as well as air pollutants.
For example, when nitrogen reacts with oxygen in the air under high temperature and pressure, it forms nitrogen oxides, which are important components in the formation of rain, as well as air pollutants. Nitrogen is also known for its ability to preserve and protect. It is commonly used in the preservation of food and pharmaceuticals.
Beyond Air Signs Agreement with MESA Specialty Gases & Equipment for Nitric Oxide and Nitrogen Dioxide Calibration Gas Supply
“With this partnership, Beyond Air has secured a critical piece of the puzzle for all of our LungFit™ systems on a global basis,” said Steve Lisi, Chairman and Chief Executive Officer of Beyond Air. “We are very impressed with the MESA team and their distribution capabilities in over 70 countries. The Beyond Air team continues to work towards ensuring the success of LungFit™.”
About NO and NO2 Calibration Gas
NO and NO2 calibration gases are manufactured solely for the purpose of calibrating sensors specific to Nitric Oxide and Nitrogen Dioxide. LungFit™ systems are all equipped with appropriate NO and NO2 sensors for monitoring proper delivery of NO and safety levels of NO2. It is standard for all NO delivery systems to be equipped with such sensors. Calibration is normally performed on a monthly basis and is an essential part of system maintenance.
About MESA Specialty Gases & Equipment
MESA Specialty Gases and Equipment, a division of MESA International Technologies, Inc. is a manufacturer and global supplier of highly accurate specialty gas and calibration gas standards used in a wide variety of instrument applications in the laboratory, energy, petrochemical and refinery industries. MESA is strategically located in Southern California near major shipping ports designed to minimize shipping costs and transit time to both domestic and international customers. Additional products include instrument grade support gases, calibration gas in small disposable cylinders and gas handling equipment. The official MESA Specialty Gases & Equipment website can be viewed at www.mesagas.com.
About Beyond Air, Inc.
Beyond Air, Inc. is a clinical-stage medical device and biopharmaceutical company developing a revolutionary NO Generator and Delivery System that uses NO generated from ambient air to deliver precise amounts of NO to the lungs for the potential treatment of a variety of pulmonary diseases. The Beyond Air NO Delivery System can generate up to 400 ppm of NO for delivery either continuously or for a fixed amount of time and has the ability to either titrate dose on demand or maintain a constant dose. The Company is currently applying its therapeutic expertise to develop treatments for pulmonary hypertension in various settings, in addition to treatments for lower respiratory tract infections that are not effectively addressed with current standards of care. Beyond Air is currently advancing its revolutionary NO Generator and Delivery System in clinical trials for the treatment of bronchiolitis and severe lung infections such as nontuberculous mycobacteria (NTM). For more information, visit www.beyondair.net.
About Nitric Oxide (NO)
Nitric Oxide (NO) is a powerful molecule proven to play a critical role in a broad array of biological functions. In the airways, NO targets the vascular smooth muscle cells that surround the small resistance arteries in the lungs and is used in adult respiratory distress syndrome and persistent pulmonary hypertension of the neonate. Additionally, NO is believed to play a key role in the innate immune system and in vitro studies suggest that NO possesses anti-microbial activity not only against common bacteria, including both gram-positive and gram-negative, but also against other diverse organisms, including mycobacteria, fungi, yeast and parasites, and has the potential to eliminate multi-drug resistant strains.
About the LungFit™ NO Generator and Delivery System*
Beyond Air’s NO Generator and Delivery System is a cylinder-free, phasic flow Nitric Oxide delivery system and has been designated as a medical device by the US Food and Drug Administration (FDA). The ventilator compatible version of the device can generate NO from ambient air on demand for delivery to the lungs at concentrations ranging from 1 part per million (ppm) to 80 ppm. The NO Generator and Delivery system could potentially replace large, high-pressure NO cylinders providing significant advantages in the hospital setting, including greatly reducing inventory and storage requirements, improving overall safety with the elimination of NO2 purging steps, and other benefits. The system can also deliver NO at concentrations above 80 ppm for which intended treatments are: bronchiolitis in the hospital setting, and chronic, refractory lung infections in the home setting. For the first time, Beyond Air intends to offer NO treatment in the home setting with the elimination of cylinders.
* Beyond Air’s LungFit™ is not approved for commercial use and Beyond Air is not suggesting use over 80 ppm or use at home. Beyond Air’s LungFit™ is for investigational purposes only.
About PPHN
Persistent pulmonary hypertension of the newborn (PPHN) is a lethal condition and a secondary to failure of normal circulatory transition at birth. It is a syndrome characterized by elevated pulmonary vascular resistance (PVR) that causes labile hypoxemia due to decreased pulmonary blood flow and right-to-left shunting of blood. Its incidence has been reported as 1.9 per 1000 live births (0.4-6.8/1000 live births) with mortality rate ranging between 4-33%. This syndrome complicates the course of about 10% of infants with respiratory failure and remains a source of considerable morbidity and mortality. NO gas is a vasodilator, is approved in dozens of countries to improve oxygenation and reduces the need for extracorporeal membrane oxygenation (ECMO) in term and near-term (>34 weeks gestation) neonates with hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension in conjunction with ventilator support and other appropriate agents.
About Bronchiolitis
The majority of hospital admissions of infants with bronchiolitis are caused by respiratory syncytial virus (RSV). RSV is a common and highly transmissible virus that infects the respiratory tract of most children before their second birthday. While most infants with RSV present with minor respiratory symptoms, a small percentage develop serious lower airway infections, termed bronchiolitis, which can become life-threatening. The absence of treatment options for bronchiolitis limits the care of these sick infants to largely supportive measures. Beyond Air’s system is designed to effectively deliver over 80 ppm NO, for which preliminary studies indicate may eliminate bacteria, viruses, fungi and other microbes from the lungs.
About NTM
Nontuberculous mycobacteria (NTM) is a rare and serious bacterial infection in the lungs causing debilitating pulmonary disease associated with increased morbidity and mortality. NTM infection is acquired by breathing in aerosolized bacteria from the environment, and if ignored can lead to NTM lung disease, a progressive and chronic condition. NTM is an emerging public health concern worldwide because of its multi-drug antibiotic resistance. Current treatment guidelines suggest a combination of multiple antibiotics delivered continually for as long as two years. These complex, expensive and invasive regimens have a poor record in the treatment of Mycobacterium abscessus complex (MABSC) and refractory Mycobacterium avium complex (MAC) and have the potential for causing severe adverse events. Beyond Air’s system is designed to effectively deliver 160 – 400 ppm NO to the lung, and early data indicate that this range of NO concentration may have a positive effect on patients infected with NTM.
Forward-Looking Statement
This press release contains “forward-looking statements.” Forward-looking statements include statements about our expectations, beliefs, or intentions regarding our product offerings, business, financial condition, results of operations, strategies or prospects. You can identify such forward-looking statements by the words “anticipates,” “expects,” “intends,” “plans,” “projects,” “believes,” “estimates,” “likely,” “goal,” “assumes,” “targets” and similar expressions and/or the use of future tense or conditional constructions (such as “will,” “may,” “could,” “should” and the like) and by the fact that these statements do not relate strictly to historical or current matters. Rather, forward-looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet occurred, these statements are inherently subject to risks and uncertainties that could cause our actual results to differ materially from any future results expressed or implied by the forward-looking statements. These forward-looking statements are only predictions and reflect our views as of the date they are made with respect to future events and financial performance. Many factors could cause our actual activities or results to differ materially from the activities and results anticipated in forward-looking statements, including risks related to: our approach to discover and develop novel drugs, which is unproven and may never lead to marketable products; our ability to fund and the results of further pre-clinical and clinical trials; obtaining, maintaining and protecting intellectual property utilized by our products; our ability to enforce our patents against infringers and to defend our patent portfolio against challenges from third parties; our ability to obtain additional funding to support our business activities; our dependence on third parties for development, manufacture, marketing, sales, and distribution of products; the successful development of our product candidates, all of which are in early stages of development; obtaining regulatory approval for products; competition from others using technology similar to ours and others developing products for similar uses; our dependence on collaborators; and our short operating history. We undertake no obligation to update, and we do not have a policy of updating or revising, these forward-looking statements, except as required by applicable law.
CONTACT
Steven Lisi, Chief Executive Officer
Beyond Air, Inc.
[email protected]
About Beyond Air, Inc.
Beyond Air, Inc. is a clinical-stage medical device and biopharmaceutical company developing a revolutionary NO Generator and Delivery System that uses NO generated from ambient air to deliver precise amounts of NO to the lungs for the potential treatment of a variety of pulmonary diseases. The Beyond Air NO Delivery System can generate up to 400 ppm of NO for delivery either continuously or for a fixed amount of time and has the ability to either titrate dose on demand or maintain a constant dose. The Company is currently applying its therapeutic expertise to develop treatments for pulmonary hypertension in various settings, in addition to treatments for lower respiratory tract infections that are not effectively addressed with current standards of care. Beyond Air is currently advancing its revolutionary NO Generator and Delivery System in clinical trials for the treatment of bronchiolitis and severe lung infections such as nontuberculous mycobacteria (NTM). For more information, visit www.beyondair.net.
By replacing the oxygen in food packaging or storage containers, nitrogen inhibits the growth of bacteria and other microorganisms that cause spoilage. This magical property of nitrogen extends the shelf life of many perishable products. Another interesting magical property of nitrogen is its use in cryogenics. Nitrogen gas can be cooled to extremely low temperatures, reaching as low as -196 degrees Celsius. This makes it a valuable tool in various industries, such as in freezing food, preserving biological samples, and even for cooling superconducting materials. Superconductors, which exhibit zero electrical resistance at low temperatures, enable the design and construction of powerful magnets and efficient electrical devices. Overall, the concept of magic mac nitrogen illustrates the unique and beneficial properties of nitrogen. Its chemical reactivity, preservative capabilities, and cryogenic properties make nitrogen a truly fascinating element. From its role in the formation of rain to its ability to prolong the shelf life of food, nitrogen continues to play a magical role in various aspects of our lives..
Reviews for "The Nitrogen-infusion Craze: What Makes Magic Macs So Magical?"
1. Sarah - 1/5 stars - I was really disappointed with "Magic Mac Nitrogen." The storyline was weak and the characters felt flat and uninteresting. It seemed like the author was trying to create a whimsical and mysterious world, but it fell flat for me. The writing style was also hard to follow at times, with confusing and disjointed sentences. I ended up giving up on the book halfway through because I just couldn't get into it.
2. Michael - 2/5 stars - I had high hopes for "Magic Mac Nitrogen" after reading positive reviews, but it just didn't live up to the hype. The plot felt unoriginal and predictable, with cliched magical elements. The characters were one-dimensional and lacked depth, making it hard for me to care about their struggles. Additionally, the pacing was incredibly slow, and I found myself bored and unengaged throughout most of the book. Overall, I was disappointed with this read.
3. Emily - 2/5 stars - I really struggled to connect with "Magic Mac Nitrogen." The writing style felt overly descriptive and flowery, which made it hard for me to engage with the story. The world-building was also confusing, with new magical concepts being introduced without proper explanations. I found myself constantly having to go back and reread sections to understand what was happening. The lack of plot development and slow pacing made the book feel like a chore to get through. Unfortunately, this one just wasn't for me.
4. David - 3/5 stars - "Magic Mac Nitrogen" had an interesting premise, but the execution fell flat for me. The story lacked a strong central conflict and failed to keep me engaged throughout. While there were some intriguing magical elements, they were overshadowed by confusing and convoluted plotlines. The prose was also overly verbose and bordered on pretentious at times. Overall, the book had the potential to be great, but it missed the mark for me.
5. Stacy - 2/5 stars - "Magic Mac Nitrogen" was a disappointing read for me. I struggled to connect with the characters, who felt underdeveloped and lacked depth. The pacing was incredibly slow, and the story often felt aimless and meandering. The magical elements introduced were interesting, but they weren't enough to salvage the book for me. While I appreciate the author's attempt at creating a unique and imaginative world, it just didn't capture my attention or interest.